Description

1,4-Cyclohexanediol, 1-Ethynyl-, trans- (8Ci,9Ci) is a specialized organic compound featuring a cyclohexanediol backbone with an ethynyl substituent. This unique structure makes it a valuable chiral building block and intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and advanced material scientists for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for sterically demanding targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators where its specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the development of specialty polymers, liquid crystals, and dendrimers requiring rigid, functionalized building blocks.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and cross-coupling protocols.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	1,4-Cyclohexanediol, 1-Ethynyl-, trans- (8Ci,9Ci)
CAS No.	1123-37-1
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	trans-1-Ethynyl-1,4-cyclohexanediol; 1,4-Cyclohexanediol, 1-ethynyl-, trans-; 1-Ethynyl-trans-1,4-cyclohexanediol; (1R,4R)-1-Ethynylcyclohexane-1,4-diol; (1S,4S)-1-Ethynylcyclohexane-1,4-diol; 1,4-Cyclohexanediol, 1-ethynyl-, (1R,4R)-rel-; 1-Ethynyl-1,4-dihydroxycyclohexane (trans)
EINECS	Contact for details

Quality Control

Our 1,4-Cyclohexanediol, 1-Ethynyl-, trans- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.