Description

(2S)-3-(o-Allyloxyphenoxy)-1,2-Epoxypropane CAS NO 66966-20-9 is a chiral, functionalized glycidyl ether derivative, serving as a versatile and high-value synthetic intermediate. Its core value lies in the reactive epoxide and allyl ether functionalities, which enable precise chemical modifications and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure building blocks for active ingredient synthesis and polymer modification.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in β-blocker and other cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where specific stereochemistry is crucial for biological activity and environmental safety.
• Advanced Polymer Chemistry: Serves as a reactive monomer or cross-linking agent for creating specialty epoxy resins, coatings, and adhesives with tailored properties.
• Liquid Crystal & OLED Materials: A precursor in the synthesis of functionalized aromatic compounds for electronic display and lighting applications.
• Asymmetric Catalysis Ligand Synthesis: Utilized for constructing complex ligand frameworks used in homogeneous catalysis.
• Fine Chemical & Flavor/Fragrance Intermediate: Employed in multi-step syntheses of complex organic molecules for high-value fine chemicals.

Basic Information

Product Name	(2S)-3-(o-Allyloxyphenoxy)-1,2-Epoxypropane
CAS No.	66966-20-9
Molecular Formula	C14H16O3
Molecular Weight	232.28 g/mol
Synonyms	(S)-(-)-1-Allyloxy-2,3-epoxypropoxybenzene; (S)-1-(Allyloxy)-2,3-epoxypropoxybenzene; (2S)-1-(Allyloxy)-2,3-epoxypropoxybenzene; (S)-Glycidyl 2-allyloxyphenyl ether; (-)-Glycidyl o-allyloxyphenyl ether; (S)-3-(2-Allyloxyphenoxy)-1,2-epoxypropane; o-Allyloxyphenyl glycidyl ether, (S)-form
EINECS	Contact for details

Quality Control

Our production of (2S)-3-(o-Allyloxyphenoxy)-1,2-Epoxypropane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. We implement GMP-compliant practices in our dedicated synthesis facilities, and specifications can be tailored to meet the rigorous demands of pharmaceutical (ICH Q7) and advanced R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.