Description

6-Fluoro-4-Chromanone is a versatile fluorinated organic building block and key chiral intermediate. This compound matters for its role in synthesizing complex molecules with enhanced biological activity and specific stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Chiral Chemistry: Serves as a valuable scaffold for constructing enantiomerically pure compounds in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and liquid crystals that require fluorinated aromatic components.
• Academic & Industrial R&D: A fundamental reagent for medicinal chemistry programs and process development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	6-Fluoro-4-Chromanone
CAS No.	66892-34-0
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	6-Fluorochroman-4-one; 4-Chromanone, 6-fluoro-; 6-Fluoro-4-chromone; 6-Fluorochromanone; 6-Fluoro-3,4-dihydro-2H-1-benzopyran-4-one; 6-Fluoro-2,3-dihydro-4H-1-benzopyran-4-one; 6-Fluoro-4H-chromen-4-one (tautomer)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Chromanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.