Description

[1Alpha,2Alpha,(E),4Alpha]-3-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Yl)Acrylic Acid CAS NO 66879-75-2 is a specialized, high-purity chiral intermediate featuring a complex bicyclic framework and an acrylic acid moiety. This compound is valued for its unique sterically hindered structure, which makes it a critical building block in advanced organic synthesis, particularly for creating molecules with specific three-dimensional architectures. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, especially those requiring rigid, sterically defined scaffolds.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with unique thermal or mechanical properties derived from its bulky bicyclic group.
• Agrochemical Intermediate: Potential use in the development of advanced crop protection agents with enhanced stereospecific activity.

Basic Information

Product Name	[1Alpha,2Alpha,(E),4Alpha]-3-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Yl)Acrylic Acid
CAS No.	66879-75-2
Molecular Formula	C₁₄H₂₀O₂
Molecular Weight	220.31 g/mol
Synonyms	(1R,2R,4R)-3-[(1R)-3,3-Dimethyl-2-norbornyl]acrylic acid; (1R,2R,4R)-3-[(1R)-3,3-Dimethylbicyclo[2.2.1]hept-2-yl]propenoic acid; (1R,2R,4R)-3-[(1R)-3,3-Dimethyl-2-norbornanyl]acrylic acid; (1R,2R,4R)-3-[(1R)-3,3-Dimethyl-2-norbornyl]acrylic acid; 3-[(1R,2S,4R)-3,3-Dimethylbicyclo[2.2.1]hept-2-yl]acrylic acid; (1R,2R,4R)-3-(3,3-Dimethylbicyclo[2.2.1]hept-2-yl)acrylic acid; (1R,2R,4R)-3-(3,3-Dimethyl-2-norbornyl)acrylic acid
EINECS	Contact for details

Quality Control

Our production of [1Alpha,2Alpha,(E),4Alpha]-3-(3,3-Dimethylbicyclo[2.2.1]Hept-2-Yl)Acrylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.