Description

(-)-2-Acetoxypropanal is a chiral, enantiomerically pure building block of significant interest in fine chemical synthesis. Its value lies in its bifunctional structure, featuring both an aldehyde and an acetate-protected alcohol, which allows for selective and sequential chemical transformations. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of complex, optically active molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of enantiomerically pure drugs, particularly those requiring specific stereochemistry for efficacy.
• Agrochemical Precursor: Used in the research and development of chiral pesticides and herbicides where biological activity is stereospecific.
• Asymmetric Synthesis Building Block: Employed in organic synthesis for constructing complex molecular architectures via aldol reactions, nucleophilic additions, and other C-C bond-forming processes.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Flavor and Fragrance Intermediate: Potential use in the synthesis of specific, high-value chiral aroma chemicals.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(-)-2-Acetoxypropanal
CAS No.	66875-70-5
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(S)-2-Acetoxypropanal; (S)-(-)-2-Acetoxypropanal; L-2-Acetoxypropanal; (S)-1-Acetoxypropan-2-one (tautomeric form); 2-Acetoxypropionaldehyde; Acetyl lactaldehyde; Acetoxyacetaldehyde, methyl-; (-)-2-Acetoxy-1-oxopropane
EINECS	Contact for details

Quality Control

Our (-)-2-Acetoxypropanal is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, assay by titration or GC, and identification by FTIR and/or NMR. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This material is easily oxidized; prolonged exposure to air or elevated temperatures should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.