Description

trans-2-Chloro-3-(Chloromethyl)Oxirane is a specialized chlorinated epoxide building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile electrophilic intermediate, enabling the introduction of functionalized oxirane and chloromethyl moieties into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring functionalized epoxide or chlorohydrin motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where its reactive epoxide ring can be opened to create novel bioactive compounds.
• Polymer & Resin Modification: Acts as a cross-linking agent or a reactive monomer for modifying epoxy resins, enhancing properties like adhesion, chemical resistance, and thermal stability.
• Fine Chemical Building Block: Employed in academic and industrial research for the development of novel chemical entities, dyes, and specialty materials.
• Surface Active Agent Precursor: Can be utilized to synthesize surfactants or coating additives with specific functional groups.

Basic Information

Product Name	trans-2-Chloro-3-(Chloromethyl)Oxirane
CAS No.	66826-73-1
Molecular Formula	C3H4Cl2O
Molecular Weight	126.97 g/mol
Synonyms	trans-1-Chloro-2-(Chloromethyl)Oxirane; 2-Chloro-3-(Chloromethyl)Oxirane; (2R,3R)-2-Chloro-3-(chloromethyl)oxirane; (2S,3S)-2-Chloro-3-(chloromethyl)oxirane; Epichlorohydrin, 2-chloro- derivative; 1-Chloro-2,3-epoxypropane, 2-chloro-; Oxirane, 2-chloro-3-(chloromethyl)-, trans-
EINECS	Contact for details

Quality Control

Our trans-2-Chloro-3-(Chloromethyl)Oxirane is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including GC, HPLC, and NMR. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and organic solvents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.