Description

3-Chloro-2-Hydroxy-2-Methylpropionic Acid [Dodecahydro-8-Hydroxy-3,6,9-Tris(Methylene)-2-Oxoazuleno[4,5-B]Furan-4-Yl] Ester is a complex, high-purity synthetic intermediate characterized by its unique fused ring structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and fine chemical products, where precise molecular architecture is paramount. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those with complex polycyclic frameworks.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides requiring specific steric and electronic properties.
• Fine Chemical Synthesis: Acts as a versatile chiral building block for constructing sophisticated molecules in catalysis and material science.
• Academic & Institutional Research: Employed in chemical biology and medicinal chemistry programs to study structure-activity relationships (SAR).
• Process Chemistry Development: Utilized for scaling up synthetic routes in pilot plants and optimizing production processes for high-value targets.

Basic Information

Product Name	3-Chloro-2-Hydroxy-2-Methylpropionic Acid [Dodecahydro-8-Hydroxy-3,6,9-Tris(Methylene)-2-Oxoazuleno[4,5-B]Furan-4-Yl] Ester
CAS No.	66761-09-9
Molecular Formula	C₂₀H₂₅ClO₆
Molecular Weight	396.86 g/mol
Synonyms	3-Chloro-2-hydroxy-2-methylpropionic acid dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester; (3aR,4S,6aS,7R,9aS,9bS)-Dodecahydro-8-hydroxy-3,6,9-tris(methylene)-2-oxoazuleno[4,5-b]furan-4-yl 3-chloro-2-hydroxy-2-methylpropanoate; CAS 66761-09-9; 3-Chloro-2-hydroxy-2-methylpropanoic acid ester with a guaiane-type sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Hydroxy-2-Methylpropionic Acid Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.