Description

2-(4-Bromobenzyl)Propanoic Acid is a versatile brominated aromatic carboxylic acid building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecules, offering a reactive handle for further functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging the bromine atom for further cross-coupling reactions.
• Liquid Crystal & OLED Material Research: Acts as a building block for creating advanced organic electronic materials and liquid crystal compounds due to its rigid aromatic core and modifiable acid group.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, thermal stability, or providing sites for further chemical grafting.
• Organic Synthesis & Catalysis Research: A valuable substrate in methodological studies for developing new catalytic processes, such as Suzuki-Miyaura or Buchwald-Hartwig cross-coupling reactions.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in chemical manufacturing.

Basic Information

Product Name	2-(4-Bromobenzyl)Propanoic Acid
CAS No.	66735-01-1
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	2-(4-Bromobenzyl)propionic Acid; 2-(p-Bromobenzyl)propanoic Acid; 4-Bromobenzylpropanoic Acid; 2-(4-Bromophenylmethyl)propanoic Acid; α-Methyl-4-bromohydrocinnamic Acid; (4-Bromobenzyl)acetic acid, α-methyl-; 66735-01-1; p-Bromobenzylpropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Bromobenzyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.