Description

1-Trifluoromethylimidazole is a high-value fluorinated heterocyclic building block essential for advanced chemical synthesis. This compound matters for its unique trifluoromethyl group, which imparts significant lipophilicity, metabolic stability, and electronic properties to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Key intermediate in the synthesis of pharmaceutical active ingredients, particularly for candidates targeting central nervous system and metabolic diseases.
• Building block for agrochemicals, including herbicides and fungicides, where the CF3 group enhances biological activity and environmental persistence.
• Precursor in the development of functional materials, such as ligands for catalysis and monomers for specialty polymers.
• Versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Used in organic synthesis to introduce the trifluoromethylimidazole moiety into complex molecular architectures.

Basic Information

Product Name	1-Trifluoromethylimidazole
CAS No.	66711-72-6
Molecular Formula	C4H3F3N2
Molecular Weight	136.08 g/mol
Synonyms	1-(Trifluoromethyl)-1H-imidazole; 1-(Trifluoromethyl)imidazole; 1H-Imidazole, 1-(trifluoromethyl)-; α,α,α-Trifluoro-N-imidazole; Trifluoromethylimidazole; 1-CF3-Imidazole; 1-Trifluoromethyl-1H-imidazole
EINECS	Contact for details

Quality Control

Our 1-Trifluoromethylimidazole CAS 66711-72-6 is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its chemical nature, it should be handled with appropriate precautions in a controlled environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.