Description

(2S,2'S)-4B,5,6,7,8,8Aβ,9,10-Octahydro-3β,9α,10β-Trihydroxy-2',4Bα,7α-Trimethyl-8-Methylenespiro[Phenanthrene-2(1H),1'-Cyclopropane]-1,4(3H)-Dione is a complex, high-purity spirocyclic diterpenoid compound of significant interest in advanced organic synthesis. Its intricate stereochemistry and functional groups make it a valuable key intermediate for the development of novel pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical R&D departments focused on exploring new chemical entities and synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-like or diterpenoid-based drug candidates.
• Advanced Organic Synthesis: Used as a chiral starting material or intermediate for constructing complex natural product analogs and spirocyclic frameworks.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) and biological pathways due to its unique molecular architecture.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in research laboratories.
• Medicinal Chemistry: A key scaffold for exploring new therapeutic agents targeting various receptors and enzymes.

Basic Information

Product Name	(2S,2'S)-4B,5,6,7,8,8Aβ,9,10-Octahydro-3β,9α,10β-Trihydroxy-2',4Bα,7α-Trimethyl-8-Methylenespiro[Phenanthrene-2(1H),1'-Cyclopropane]-1,4(3H)-Dione
CAS No.	66674-61-1
Molecular Formula	C22H30O5
Molecular Weight	374.47 g/mol
Synonyms	8-Methylenespiro[phenanthrene-2(1H),1'-cyclopropane]-1,4(3H)-dione, 4b,5,6,7,8,8aβ,9,10-octahydro-3β,9α,10β-trihydroxy-2',4bα,7α-trimethyl-, (2S,2'S)-; 7α-Hydroxy-8-methylene-13-methyl-14,15-dinor-5β,8α,9β,10α-labdan-6-one; A related diterpenoid spiroketal intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.