Description

D-Aspartic Acid, 3-Chloro-, Diethyl Ester, Hydrochloride, (3S)-Rel- (9Ci) CAS NO 66619-95-2 is a high-purity, chiral synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the preparation of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require precise stereochemistry and functional group manipulation for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in neurological and metabolic disorder research.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics where the chloro and ester functionalities allow for further chemical elaboration.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Biochemical Research: Employed in studies of enzyme inhibitors and receptor ligands due to its structural similarity to natural aspartic acid derivatives.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemical configurations.

Basic Information

Product Name	D-Aspartic Acid, 3-Chloro-, Diethyl Ester, Hydrochloride, (3S)-Rel- (9Ci)
CAS No.	66619-95-2
Molecular Formula	C8H15Cl2NO4
Molecular Weight	260.11 g/mol
Synonyms	(3S)-3-Chloro-D-aspartic Acid Diethyl Ester Hydrochloride; Diethyl (3S)-3-Chloro-D-aspartate Hydrochloride; D-3-Chloroaspartic Acid Diethyl Ester Hydrochloride; (2S)-2-Amino-3-chlorobutanedioic Acid 1,4-Diethyl Ester Hydrochloride; (3S)-rel-3-Chloro-D-aspartic Acid Diethyl Ester Hydrochloride; L-? (Note: Verify stereochemistry designation per specific customer requirement).
EINECS	Contact for details

Quality Control

Our D-Aspartic Acid, 3-Chloro-, Diethyl Ester, Hydrochloride, (3S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.