Description

Methyl Gestodene CAS NO 66452-30-0 is a synthetic progestin steroid, specifically a 17α-methyl derivative of gestodene. This compound is a key pharmaceutical intermediate of significant interest in the development of advanced hormonal therapies. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel contraceptive and hormone replacement formulations.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation progestin-based active pharmaceutical ingredients (APIs).
• Contraceptive Research: Used in the development and study of new oral contraceptive formulations with potentially improved efficacy and side-effect profiles.
• Hormone Replacement Therapy (HRT): Serves as a precursor in research for HRT products aimed at treating menopausal symptoms.
• Endocrinology Studies: Employed as a reference standard or test compound in biochemical and pharmacological research on progesterone receptor activity.
• Process Development: Utilized by process chemistry teams for scaling up synthesis routes and optimizing manufacturing protocols for steroid-based drugs.

Basic Information

Product Name	Methyl Gestodene
CAS No.	66452-30-0
Molecular Formula	C22H28O2
Molecular Weight	324.46 g/mol
Synonyms	17α-Methylgestodene; 13-Ethyl-17α-methyl-17-hydroxy-11-methylene-18,19-dinor-4,15-pregnadien-20-yn-3-one; 17α-Methyl-11-methylene-19-nor-17-pregna-4,15-dien-20-yn-3-one; Methylgestodene; Gestodene 17α-methyl derivative
EINECS	Contact for details

Quality Control

Our Methyl Gestodene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.