Description

Forskolin is a bioactive labdane diterpene compound primarily extracted from the roots of the Indian Coleus plant (*Coleus forskohlii*). This versatile molecule is a potent activator of the enzyme adenylate cyclase, leading to increased intracellular levels of cyclic AMP (cAMP), which regulates numerous cellular functions. It is a critical raw material for the pharmaceutical, nutraceutical, and life science research industries, where it is valued for its role in metabolic and cardiovascular research, as well as in dietary supplement formulations.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or active pharmaceutical ingredient (API) in the development of drugs targeting metabolic disorders, cardiovascular conditions, and glaucoma.
• Dietary Supplements & Nutraceuticals: Widely used in weight management and sports nutrition formulations for its potential to support healthy metabolism and lean body mass.
• Biochemical & Life Science Research: An essential tool compound in cell biology and pharmacology for studying cAMP-mediated signaling pathways, ion channel function, and enzyme activation.
• Cosmeceutical Ingredients: Incorporated into topical formulations for its potential benefits in promoting healthy skin and hair.
• Veterinary Applications: Used in research and development of animal health products.

Basic Information

Product Name	Forskolin
CAS No.	66428-89-5
Molecular Formula	C22H34O7
Molecular Weight	410.50 g/mol
Synonyms	Coleonol; 1α,6β,9α-Trihydroxy-8,13-epoxy-labd-14-en-11-one; 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one; NKH477 (hydrochloride derivative); MaofSK; Colforsin; HL-362
EINECS	Contact for details

Quality Control

Our Forskolin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with relevant standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.