Description

5-Methyl-2-Nitrobenzyl Chloride is a versatile and reactive aromatic building block, primarily valued for its benzyl chloride and nitro functional groups. This compound is essential for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research and development. It is a key intermediate for scientists and manufacturers in the fine chemical, pharmaceutical, and material science industries seeking to introduce specific functional groups into their target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where its nitro and benzyl chloride groups enable further chemical modifications.
• Dye and Pigment Manufacturing: Serves as a building block for creating complex organic dyes and colorants due to its aromatic nitro structure.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Nucleophilic Substitution: The reactive benzyl chloride group allows for facile substitution with various nucleophiles like amines, alkoxides, and thiols to create diverse chemical libraries.

Basic Information

Product Name	5-Methyl-2-Nitrobenzyl Chloride
CAS No.	66424-91-7
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Nitro-5-methylbenzyl chloride; 1-(Chloromethyl)-2-nitro-5-methylbenzene; (2-Nitro-5-methylphenyl)methyl chloride; 5-Methyl-2-nitrobenzylchloride; 2-Nitro-5-methylbenzylchloride; α-Chloro-2-nitro-5-methyltoluene
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Nitrobenzyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.