Description

2,5,5-Trimethyl-1,3,2-Dioxaborinane CAS NO 66423-62-9 is a versatile cyclic boronic ester, valued for its role as a protected boronic acid equivalent and a key reagent in advanced organic synthesis. Its primary commercial value lies in enabling efficient cross-coupling reactions, which are fundamental to constructing complex molecules in research and industrial settings. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity, reactive intermediates for developing active ingredients and novel polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A crucial protected boronic acid precursor for forming carbon-carbon bonds in pharmaceutical and fine chemical synthesis.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Polymer & Materials Science: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing boron-containing functional groups into target molecules.
• Research & Development: A valuable tool for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Item	Detail
Product Name	2,5,5-Trimethyl-1,3,2-Dioxaborinane
CAS No.	66423-62-9
Molecular Formula	C6H13BO2
Molecular Weight	128.98 g/mol
Synonyms	2,5,5-Trimethyl-1,3,2-dioxaborinane; Trimethyldioxaborinane; Pinacolborane Methyl Ether Derivative; Cyclic Methyl Boronate; 1,3,2-Dioxaborinane, 2,5,5-trimethyl-; B-Methoxyborinane; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2,5,5-Trimethyl-1,3,2-Dioxaborinane is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or 11B NMR)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.