Description

2',2,2,5'-Tetramethylpropiophenone is a specialized organic compound belonging to the propiophenone class, characterized by its unique tetramethyl substitution pattern. This structural feature makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific steric and electronic properties. It is primarily sought by research and development laboratories and industrial chemists in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those requiring bulky, lipophilic aromatic groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its specific structure can influence biological activity and selectivity.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers, liquid crystals, or organic electronic materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs or other fine chemicals via various coupling and functionalization reactions.
• Photoinitiator Component: Can be investigated as a component in UV-curing systems for inks, coatings, and adhesives due to its benzophenone-related structure.
• Flavor & Fragrance Intermediate: Potentially used in the synthesis of complex aroma chemicals where the tetramethyl substitution imparts specific olfactory characteristics.

Basic Information

Product Name	2',2,2,5'-Tetramethylpropiophenone
CAS No.	66390-56-5
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	2,2,5-Trimethyl-1-phenylpentan-1-one; 1-Phenyl-2,2,5-trimethylpentan-1-one; 2,2,5-Trimethyl-1-phenyl-1-pentanone; Propiophenone, 2',2,2,5'-tetramethyl-; α,α,β-Trimethyl-γ-phenylbutyrophenone (possible misnomer); Tetramethylpropiophenone
EINECS	Contact for details

Quality Control

Our 2',2,2,5'-Tetramethylpropiophenone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.