Description

1-(4-Chlorophenyl)-4,4-Dimethyl-3-Pentanone is a versatile chlorinated ketone intermediate of significant importance in advanced organic synthesis. This compound is valued for its unique molecular structure, which serves as a key building block for the development of more complex chemical entities. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a key precursor in the development of advanced pesticides, herbicides, and plant growth regulators, leveraging the chlorophenyl moiety for bioactivity.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for method development, catalysis studies, and the creation of complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including dyes, pigments, and performance materials where specific chlorinated ketone functionality is required.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.

Basic Information

Product Name	1-(4-Chlorophenyl)-4,4-Dimethyl-3-Pentanone
CAS No.	66346-01-8
Molecular Formula	C13H17ClO
Molecular Weight	224.73 g/mol
Synonyms	4'-Chloro-2,2-dimethylpropiophenone; 1-(4-Chlorophenyl)-4,4-dimethylpentan-3-one; 4-Chlorophenyl neopentyl ketone; p-Chlorophenyl tert-butyl ketone; 4-Chloro-α,α-dimethylpropiophenone; NSC 403116; tert-Butyl 4-chlorophenyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-4,4-Dimethyl-3-Pentanone is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.