Description

2-(sec-Butyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, organoboron reagent belonging to the class of pinacol boronic esters. This compound is a versatile and critical building block in modern synthetic chemistry, valued for its stability and reactivity in cross-coupling reactions. It is primarily used by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to construct complex molecular architectures. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your critical applications.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and boronic esters, essential for synthesizing biaryl structures in drug discovery and material science.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), enabling the introduction of the sec-butyl moiety into complex molecules.
• Agrochemical Active Ingredient Development: Employed in creating novel herbicides, fungicides, and insecticides by constructing specific alkyl-substituted aromatic cores.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor in the synthesis of electron-transport or host materials for display and lighting technologies.
• Polymer and Functional Material Chemistry: Used to incorporate boron-containing functional groups into polymers or small molecules for specialty materials.
• Chemical Biology & Medicinal Chemistry: Acts as a probe or intermediate in the development of enzyme inhibitors and other biologically active compounds.

Basic Information

Product Name	2-(sec-Butyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	66217-57-0
Molecular Formula	C₁₀H₂₁BO₂
Molecular Weight	184.09 g/mol
Synonyms	sec-Butylboronic Acid Pinacol Ester; (1-Methylpropyl)boronic Acid Pinacol Ester; 2-(1-Methylpropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol sec-Butylboronate; sec-ButylBpin; B-(sec-Butyl)pinacolborane; 66217-57-0; sec-Butylboronic Acid Pinacol Cyclic Ester
EINECS	Contact for details

Quality Control

Every batch of 2-(sec-Butyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure the product meets the high-purity standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.