Description

2-Cyclopentyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity, cyclic boronic ester derivative valued for its stability and reactivity as a versatile synthetic building block. This compound is essential for facilitating key carbon-carbon bond-forming reactions in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to construct complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for palladium-catalyzed cross-coupling to form biaryl and other C-C bonds, a cornerstone of modern medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Product Development: Employed in the synthesis of advanced herbicides, fungicides, and insecticides requiring specific boronic ester intermediates.
• Materials Science & OLED Research: Serves as a precursor for creating organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Synthesis: Acts as a handle for bioconjugation and the synthesis of molecular probes for biochemical assays.

Basic Information

Product Name	2-Cyclopentyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	66217-55-8
Molecular Formula	C11H21BO2
Molecular Weight	196.10 g/mol
Synonyms	Cyclopentylboronic acid pinacol ester; Cyclopentyl-BPin; Cyclopentaneboronic acid pinacol ester; 2-Cyclopentyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclopentyl pinacol boronate; CyclopentylBPin; Cyclopentylboronate pinacol ester; Cyclopentylboronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Cyclopentyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and lot-to-lot consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.