Description

Bromomethyl -Phosphonic Acid Diethyl Ester is a versatile organophosphorus compound, specifically a phosphonate ester, that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, featuring both a reactive bromomethyl group and a protected phosphonic acid moiety, enabling its use in the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of biologically active molecules and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bisphosphonate drugs and other active pharmaceutical ingredients (APIs) targeting bone metabolism disorders.
• Agrochemical Synthesis: Building block for creating novel herbicides, plant growth regulators, and other crop protection agents with phosphonate backbones.
• Ligand and Catalyst Preparation: Used to synthesize phosphonate-based ligands for metal catalysis and organocatalysts.
• Material Science: Intermediate for producing flame retardants, polymer modifiers, and specialty surfactants.
• Peptide Mimetics & Prodrugs: Employed in medicinal chemistry to create phosphonate-based peptide analogs and prodrug systems.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological processes.

Basic Information

Product Name	Bromomethyl -Phosphonic Acid Diethyl Ester
CAS No.	66197-72-6
Molecular Formula	C5H12BrO3P
Molecular Weight	231.03 g/mol
Synonyms	Diethyl (bromomethyl)phosphonate; (Bromomethyl)phosphonic Acid Diethyl Ester; Diethyl Bromomethylphosphonate; Bromomethylphosphonic Acid Diethyl Ester; (Bromomethylene)diethyl phosphonate; Diethyl P-(bromomethyl)phosphonate; NSC 169084; BRP
EINECS	Contact for details

Quality Control

Our Bromomethyl -Phosphonic Acid Diethyl Ester is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.