Description

Cimicifugoside is a triterpenoid glycoside primarily isolated from the roots of the *Cimicifuga* (Actaea) species, such as Black Cohosh. This compound matters for its significant role as a key bioactive marker in botanical extracts used for quality standardization and pharmacological research. It is needed by manufacturers in the pharmaceutical, nutraceutical, and research sectors for developing standardized herbal formulations and reference standards.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and assay of Black Cohosh extracts and finished products.
• Nutraceutical Formulation: Serves as a key marker compound for standardizing botanical dietary supplements, ensuring consistent potency and efficacy.
• Pharmacological Research: Employed in in vitro and in vivo studies to investigate potential biological activities, including effects on hormonal pathways.
• Analytical Chemistry: Utilized as an analytical standard in methods like HPLC and LC-MS for the identification and quantification of triterpene glycosides in complex matrices.
• Herbal Extract Production: Acts as a target compound for the optimization of extraction and purification processes from Black Cohosh raw material.

Basic Information

Product Name	Cimicifugoside
CAS No.	66176-93-0
Molecular Formula	C37H56O11
Molecular Weight	676.84 g/mol
Synonyms	27-Deoxyactein; Cimigenol 3-O-β-D-xylopyranoside; (23R,24S)-16,23:16,24-Diepoxy-12β-acetoxy-3β-(β-D-xylopyranosyloxy)-9,19-cyclolanost-25-en-7-one; 27-Deoxyacetylacteol; Actein impurity
EINECS	Contact for details

Quality Control

Our Cimicifugoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets high-purity standards suitable for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.