Description

L-Alanine, 2-(4-Chlorophenyl)-1,1-Dimethylethyl Ester is a specialized chiral amino acid derivative, valued for its role as a key synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring a protected alanine moiety and a chlorophenyl group, makes it a critical building block for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of novel Active Pharmaceutical Ingredients (APIs), especially in therapeutic areas requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the chlorophenyl and amino acid ester functionalities contribute to biological activity.
• Peptidomimetics & Drug Discovery: Serves as a protected amino acid building block in solid-phase peptide synthesis (SPPS) and the creation of peptide analogs for medicinal chemistry research.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers and functional materials with unique properties.

Basic Information

Product Name	L-Alanine, 2-(4-Chlorophenyl)-1,1-Dimethylethyl Ester
CAS No.	66171-75-3
Molecular Formula	C₁₄H₁₈ClNO₂
Molecular Weight	267.75 g/mol
Synonyms	L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-4-chloro-β-methyl-; tert-Butyl (2S)-2-[(4-chlorophenyl)methyl]propanoate; (S)-2-((4-Chlorobenzyl)propanoic acid tert-butyl ester; BOC-L-4-Chloro-β-methylphenylalanine tert-butyl ester; N-BOC-4-Chloro-β-methyl-L-phenylalanine tert-butyl ester; (S)-tert-Butyl 2-(4-chlorobenzyl)propanoate; Alanine derivative with 4-chlorophenyl and tert-butyl ester groups
EINECS	Contact for details

Quality Control

Our L-Alanine, 2-(4-Chlorophenyl)-1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.