Description

Ethanone, 2-Chloro-1-(2-Fluoro-5-Methylphenyl)- (9Ci) is a specialized aromatic ketone derivative, identified by CAS number 66122-32-5, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing fluorinated and chlorinated aromatic systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands that can modulate catalytic activity in cross-coupling and other transition metal-catalyzed reactions.
• Fluorine Chemistry Studies: Acts as a model substrate in methodological development for introducing and manipulating fluorine atoms in complex molecules.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector, enabling the production of bespoke compounds for client research programs.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(2-Fluoro-5-Methylphenyl)- (9Ci)
CAS No.	66122-32-5
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	2-Chloro-1-(2-fluoro-5-methylphenyl)ethanone; 2'-Fluoro-5'-methyl-2-chloroacetophenone; 1-(2-Fluoro-5-methylphenyl)-2-chloroethanone; α-Chloro-2'-fluoro-5'-methylacetophenone; 2-Chloro-2'-fluoro-5'-methylacetophenone; 66122-32-5; Acetophenone, 2-chloro-1-(2-fluoro-5-methylphenyl)-
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-(2-Fluoro-5-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance as a synthetic intermediate. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.