Description

4-Phenyltetrahydro-2H-Pyran-4-Carboxaldehyde is a versatile aldehyde-substituted heterocyclic compound that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring a phenyl group and a formyl moiety on a tetrahydropyran ring, makes it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and functional organic materials with specific optical or electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex aroma chemicals due to its aldehyde functionality and stable cyclic structure.

Basic Information

Product Name	4-Phenyltetrahydro-2H-Pyran-4-Carboxaldehyde
CAS No.	66109-88-4
Molecular Formula	C₁₂H₁₄O₂
Molecular Weight	190.24 g/mol
Synonyms	4-Phenyltetrahydro-2H-pyran-4-carboxaldehyde; 4-Formyl-4-phenyltetrahydropyran; 4-Phenyl-4-formyltetrahydropyran; 4-Phenyltetrahydropyran-4-carbaldehyde; 4-Phenyl-4-tetrahydropyrancarboxaldehyde; 4-Phenyl-4-(tetrahydro-2H-pyran-4-yl)carbaldehyde; 66109-88-4
EINECS	Contact for details

Quality Control

Our 4-Phenyltetrahydro-2H-Pyran-4-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep container tightly sealed under an inert gas blanket (e.g., nitrogen or argon) to minimize oxidation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.