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Poly(Ethyleneglycol-Lactide) CAS NO 66082-05-1


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CAS No.:66082-05-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Poly(Ethyleneglycol-Lactide) is a biocompatible and biodegradable block copolymer synthesized from polyethylene glycol (PEG) and polylactide (PLA) segments. This unique structure provides a versatile platform material with tunable hydrophilicity, degradation rate, and mechanical properties, making it critical for advanced formulation and controlled-release technologies. It is primarily needed by manufacturers in the pharmaceutical, biomedical, and specialty chemical industries for developing drug delivery systems, tissue engineering scaffolds, and functional polymeric materials.

Application

  • Controlled Drug Delivery Systems: As a key excipient for creating micelles, nanoparticles, and hydrogels for sustained and targeted release of active pharmaceutical ingredients (APIs).
  • Biomedical Implants & Tissue Engineering: Used in the fabrication of biodegradable scaffolds, sutures, and matrices that support cell growth and tissue regeneration.
  • Functional Polymer Synthesis: Serves as a macro-initiator or building block for creating advanced amphiphilic copolymers with specific surface properties.
  • Cosmetic & Personal Care Formulations: Employed as a film-forming agent, emulsifier, or carrier for active ingredients in premium skincare products.
  • Specialty Adhesives and Coatings: Utilized in the development of bio-based, degradable adhesives and coatings for medical or eco-friendly applications.
  • Research & Development: A fundamental material for academic and industrial R&D exploring new biodegradable polymers and nano-formulations.

Basic Information

Product Name Poly(Ethyleneglycol-Lactide)
CAS No. 66082-05-1
Molecular Formula (C2H4O)m(C3H4O2)n
Molecular Weight Variable (Depends on m:n ratio and block lengths)
Synonyms PEG-PLA; PLA-PEG; Poly(lactide)-block-poly(ethylene glycol); Poly(ethylene glycol)-block-poly(lactide); Poly(lactic acid)-poly(ethylene glycol) copolymer; PEG-Polylactide; Polylactide-Polyethylene Glycol Block Copolymer; Poly(D,L-lactide)-b-poly(ethylene glycol)
EINECS Contact for details

Quality Control

Our Poly(Ethyleneglycol-Lactide) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency in molecular weight, composition, and purity, meeting the high standards required for pharmaceutical and biomedical applications. Certificates of Analysis (COA) detailing specifications such as block ratio, polydispersity index (PDI), and residual monomer content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product performance. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (IR) Conforms to structure
Composition (PEG:PLA ratio) As per customer grade (e.g., 50:50, 70:30)
Molecular Weight (GPC) Specified range (e.g., 2000 - 10000 Da)
Polydispersity Index (PDI) ≤ 1.5
Residual Solvent (GC) Meets ICH guidelines
Residual Monomer (HPLC) < 1.0%
Water Content (KF) < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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