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Poly(Ethyleneglycol-Lactide) CAS NO 66082-05-1
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CAS No.:66082-05-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Poly(Ethyleneglycol-Lactide) is a biocompatible and biodegradable block copolymer synthesized from polyethylene glycol (PEG) and polylactide (PLA) segments. This unique structure provides a versatile platform material with tunable hydrophilicity, degradation rate, and mechanical properties, making it critical for advanced formulation and controlled-release technologies. It is primarily needed by manufacturers in the pharmaceutical, biomedical, and specialty chemical industries for developing drug delivery systems, tissue engineering scaffolds, and functional polymeric materials.
Application
- Controlled Drug Delivery Systems: As a key excipient for creating micelles, nanoparticles, and hydrogels for sustained and targeted release of active pharmaceutical ingredients (APIs).
- Biomedical Implants & Tissue Engineering: Used in the fabrication of biodegradable scaffolds, sutures, and matrices that support cell growth and tissue regeneration.
- Functional Polymer Synthesis: Serves as a macro-initiator or building block for creating advanced amphiphilic copolymers with specific surface properties.
- Cosmetic & Personal Care Formulations: Employed as a film-forming agent, emulsifier, or carrier for active ingredients in premium skincare products.
- Specialty Adhesives and Coatings: Utilized in the development of bio-based, degradable adhesives and coatings for medical or eco-friendly applications.
- Research & Development: A fundamental material for academic and industrial R&D exploring new biodegradable polymers and nano-formulations.
Basic Information
| Product Name | Poly(Ethyleneglycol-Lactide) |
| CAS No. | 66082-05-1 |
| Molecular Formula | (C2H4O)m(C3H4O2)n |
| Molecular Weight | Variable (Depends on m:n ratio and block lengths) |
| Synonyms | PEG-PLA; PLA-PEG; Poly(lactide)-block-poly(ethylene glycol); Poly(ethylene glycol)-block-poly(lactide); Poly(lactic acid)-poly(ethylene glycol) copolymer; PEG-Polylactide; Polylactide-Polyethylene Glycol Block Copolymer; Poly(D,L-lactide)-b-poly(ethylene glycol) |
| EINECS | Contact for details |
Quality Control
Our Poly(Ethyleneglycol-Lactide) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency in molecular weight, composition, and purity, meeting the high standards required for pharmaceutical and biomedical applications. Certificates of Analysis (COA) detailing specifications such as block ratio, polydispersity index (PDI), and residual monomer content are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product performance. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or waxy solid |
| Identification (IR) | Conforms to structure |
| Composition (PEG:PLA ratio) | As per customer grade (e.g., 50:50, 70:30) |
| Molecular Weight (GPC) | Specified range (e.g., 2000 - 10000 Da) |
| Polydispersity Index (PDI) | ≤ 1.5 |
| Residual Solvent (GC) | Meets ICH guidelines |
| Residual Monomer (HPLC) | < 1.0% |
| Water Content (KF) | < 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






