Description

Glycyrrhetinic Acid 3-o-Hemiphthalate is a chemically modified derivative of glycyrrhetinic acid, a key bioactive compound from licorice root. This esterification enhances its stability and solubility profile, making it a valuable intermediate for advanced pharmaceutical and cosmetic formulations. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and high-end personal care industries for developing targeted therapeutic and skin-enhancing products.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel anti-inflammatory and hepatoprotective drugs.
• Cosmetic Actives: A key ingredient in premium skincare formulations for its soothing, anti-irritant, and skin-brightening properties.
• Nutraceutical Research: Employed in the development of dietary supplements targeting digestive and metabolic health.
• Biochemical Research: Serves as a standard or reagent in studies investigating steroid-like activity and enzyme inhibition.
• Advanced Drug Delivery Systems: Utilized to improve the bioavailability and targeted release of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Glycyrrhetinic Acid 3-o-Hemiphthalate
CAS No.	66067-20-7
Molecular Formula	C38H48O7
Molecular Weight	616.79 g/mol
Synonyms	3-O-Hemiphthaloyl Glycyrrhetinic Acid; Glycyrrhetinic Acid Hemiphthalate; Enoxolone 3-O-Hemiphthalate; 3β-Hydroxy-11-oxoolean-12-en-30-oic acid 3-hemiphthalate; (3β)-3-(Carboxybenzoyl)oxy-11-oxoolean-12-en-30-oic Acid; GAHP; 18β-Glycyrrhetinic Acid 3-O-Hemiphthalate
EINECS	Contact for details

Quality Control

Our Glycyrrhetinic Acid 3-o-Hemiphthalate is produced under strict quality management systems. Each batch is tested to ensure high purity and consistency, meeting the rigorous standards required for pharmaceutical and cosmetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term preservation and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.