Description

1,1,1,3,3,3-Hexafluoro-2-(1,2,3,4-Tetrahydro-Quinolin-6-Yl)-Propan-2-Ol is a high-value fluorinated organic intermediate featuring a unique combination of a hexafluoroisopropanol group and a tetrahydroquinoline moiety. This compound is critical for its role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its fluorine content and rigid structure impart desirable properties like metabolic stability and lipophilicity. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, reduce surface energy, and improve material performance.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing complex fluorinated molecular architectures.
• Advanced Material Research: Investigated for use in organic electronics and as a component in high-performance coatings.

Basic Information

Product Name	1,1,1,3,3,3-Hexafluoro-2-(1,2,3,4-Tetrahydro-Quinolin-6-Yl)-Propan-2-Ol
CAS No.	65797-52-6
Molecular Formula	C₁₂H₁₁F₆NO
Molecular Weight	299.21 g/mol
Synonyms	6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinoline; 2-(1,2,3,4-Tetrahydro-6-quinolinyl)-1,1,1,3,3,3-hexafluoro-2-propanol; Hexafluoro-2-(tetrahydroquinolin-6-yl)propan-2-ol; 1,1,1,3,3,3-Hexafluoro-2-(1,2,3,4-tetrahydroquinolin-6-yl)propan-2-ol; HFIP-Tetrahydroquinoline Derivative
EINECS	Contact for details

Quality Control

Our production of 1,1,1,3,3,3-Hexafluoro-2-(1,2,3,4-Tetrahydro-Quinolin-6-Yl)-Propan-2-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.