Description

4-(Trifluoromethoxy)Benzyl Chloride is a versatile and high-value organofluorine building block, essential for introducing the 4-(trifluoromethoxy)benzyl moiety into complex molecular architectures. Its primary commercial value lies in enabling the synthesis of advanced agrochemicals and pharmaceuticals with enhanced biological activity and metabolic stability. This intermediate is critically needed by R&D and production chemists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: Key precursor for synthesizing modern pesticides, herbicides, and fungicides, where the trifluoromethoxy group improves lipophilicity and target binding.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated aromatic systems for improved drug efficacy and pharmacokinetics.
• Liquid Crystal Materials: Serves as a starting material in the production of fluorinated liquid crystals for advanced display technologies.
• Functional Polymer Synthesis: Employed to incorporate fluorinated aromatic units into polymers, enhancing their chemical resistance, thermal stability, and optical properties.
• Organic Synthesis Reagent: A valuable reagent in organic chemistry for nucleophilic substitution reactions, enabling the benzylation of various nucleophiles.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzyl Chloride
CAS No.	65796-00-1
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	α-Chloro-4-(trifluoromethoxy)toluene; 1-(Chloromethyl)-4-(trifluoromethoxy)benzene; (4-(Trifluoromethoxy)phenyl)methyl chloride; 4-(Trifluoromethoxy)benzylchloride; p-(Trifluoromethoxy)benzyl Chloride; 4-(Trifluoromethoxy)benzyl Chloride; 4-(Trifluoromethoxy)benzylchloride; 65796-00-1
EINECS	265-938-4

Quality Control

Our 4-(Trifluoromethoxy)Benzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.