Description

(E)-3-(4-Bromophenyl)-1-(2-Hydroxyphenyl)- 2-Propen-1-One CAS NO 65786-14-3 is a high-purity chalcone derivative, a key organic intermediate characterized by its distinct α,β-unsaturated ketone structure. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the creation of complex molecules with tailored properties. It is primarily sought after by research institutions and pharmaceutical development companies for applications in medicinal chemistry, material science, and as a precursor for novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies due to its modifiable bromo and hydroxy functional groups.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential electron-transport or emissive layer material in optoelectronic devices.
• Ligand Synthesis: Acts as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of fluorescent or bioactive probes for studying biological pathways.
• Material Science: Employed in the synthesis of advanced polymers and functional organic materials with specific optical properties.

Basic Information

Product Name	(E)-3-(4-Bromophenyl)-1-(2-Hydroxyphenyl)- 2-Propen-1-One
CAS No.	65786-14-3
Molecular Formula	C15H11BrO2
Molecular Weight	303.15 g/mol
Synonyms	3-(4-Bromophenyl)-1-(2-hydroxyphenyl)-2-propen-1-one; (E)-1-(2-Hydroxyphenyl)-3-(4-bromophenyl)prop-2-en-1-one; 4'-Bromo-2'-hydroxychalcone; 2-Hydroxy-4'-bromochalcone; (E)-3-(p-Bromophenyl)-1-(o-hydroxyphenyl)-2-propen-1-one; NSC 403914; p-Bromo-o-hydroxychalcone
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Bromophenyl)-1-(2-Hydroxyphenyl)- 2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to reliable quality supports critical research and development projects globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.