Description

3,4-(Methylenedioxy)Phenylglyoxal Hydrate is a high-value, versatile chemical building block characterized by its reactive glyoxal and methylenedioxy functional groups. This compound matters for its critical role as a key intermediate in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic scaffolds, including benzofurans and quinazolines, for potential drug discovery and API manufacturing.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive sites to create complex molecular architectures with specific biological activity.
• Fine Chemical Production: Serves as a specialized building block for synthesizing dyes, pigments, and advanced materials requiring the methylenedioxybenzene motif.
• Bioconjugation & Labeling Reagent: The reactive carbonyl groups can be utilized for modifying proteins, peptides, or other biomolecules in biochemical research.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical reactions.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel chelating ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3,4-(Methylenedioxy)Phenylglyoxal Hydrate
CAS No.	65709-23-1
Molecular Formula	C9H8O5 • xH2O
Molecular Weight	196.16 (Anhydrous basis)
Synonyms	1,2-Dioxo-2-(3,4-methylenedioxyphenyl)ethane Hydrate; 3,4-Methylenedioxyphenylglyoxal Hydrate; Piperonylglyoxal Hydrate; (3,4-Methylenedioxyphenyl)oxoacetaldehyde Hydrate; 1-(1,3-Benzodioxol-5-yl)-1,2-ethanedione Hydrate; 2-Oxo-2-(1,3-benzodioxol-5-yl)acetaldehyde Hydrate; NSC 404058
EINECS	Contact for details

Quality Control

Our 3,4-(Methylenedioxy)Phenylglyoxal Hydrate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.