Description

7-Oxooctanoic Acid, 2-Trimethylsilylethyl Ester is a high-purity, protected keto-acid derivative, serving as a versatile and critical synthetic intermediate in advanced organic chemistry. Its value lies in the dual functionality of the ketone and ester groups, protected by a robust 2-trimethylsilylethyl group, which allows for selective deprotection under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex molecules, peptide mimetics, and specialized polymers where precise control over molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing keto-acid or protected carboxylic acid motifs.
• Peptide Chemistry: Used in the preparation of modified amino acids and peptide analogs where the protected ester is crucial for solid-phase or solution-phase synthesis strategies.
• Fine Chemical Synthesis: Serves as a precursor for fragrances, flavors, and other specialty organic compounds requiring the introduction of a keto-octanoic acid chain.
• Polymer Science: Acts as a monomer or co-monomer for creating functionalized polymers with specific degradation profiles or side-chain reactivity.
• Material Science Research: Employed in the development of novel organic materials, surface modifiers, and ligands for catalysis.
• Bioconjugation: Useful in linker chemistry for attaching molecules to biomolecules, where the protected ester allows for later-stage activation.

Basic Information

Item	Details
Product Name	7-Oxooctanoic Acid, 2-Trimethylsilylethyl Ester
CAS No.	65690-30-4
Molecular Formula	C13H26O3Si
Molecular Weight	258.43 g/mol
Synonyms	2-(Trimethylsilyl)ethyl 7-oxooctanoate; 7-Oxo-octanoic acid 2-trimethylsilylethyl ester; 2-Trimethylsilylethyl 7-oxooctanoate; Octanoic acid, 7-oxo-, 2-(trimethylsilyl)ethyl ester; TES-Protected 7-Oxooctanoic Acid; (2-Trimethylsilylethyl) 7-oxooctanoate
EINECS	Contact for details

Quality Control

Our 7-Oxooctanoic Acid, 2-Trimethylsilylethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and spectroscopic identification. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.