Description

4-(Heptafluoropropylsulfonyl)Chlorobenzene is a high-value fluorinated aromatic sulfonyl chloride intermediate, distinguished by its unique perfluorinated alkyl chain. This compound is critical for introducing the heptafluoropropylsulfonyl moiety, a key functional group that imparts enhanced stability, lipophilicity, and electronic properties to target molecules. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and specialty chemicals. Its role as a building block enables the development of products with tailored performance characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing sulfonamide-based drugs with improved metabolic stability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorinated sulfonyl group enhances biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, coatings, and liquid crystals with unique surface properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to introduce the heptafluoropropylsulfonyl group into complex organic frameworks.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorinated compounds for electronic and optoelectronic applications.

Basic Information

Product Name	4-(Heptafluoropropylsulfonyl)Chlorobenzene
CAS No.	65538-06-9
Molecular Formula	C9H4ClF7O2S
Molecular Weight	332.63 g/mol
Synonyms	1-Chloro-4-(heptafluoropropylsulfonyl)benzene; 4-Chlorophenyl heptafluoropropyl sulfone; p-Chlorophenyl perfluoropropyl sulfone; Heptafluoropropyl 4-chlorophenyl sulfone; Benzene, 1-chloro-4-[(1,1,2,2,3,3,3-heptafluoropropyl)sulfonyl]-; 4-Chloro-1-(heptafluoropropane-1-sulfonyl)benzene; 4-(Perfluoropropylsulfonyl)chlorobenzene
EINECS	Contact for details

Quality Control

Our production of 4-(Heptafluoropropylsulfonyl)Chlorobenzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistency and reliability. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.