Description

Poly(Difluoromethylene), .Alpha.-Fluoro-.Omega.-2-(Phosphonooxy)Ethyl- is a specialized fluorinated organophosphorus compound, identified by CAS No. 65530-61-2. This chemical is valued for its unique molecular architecture, which combines a fluorinated backbone with a reactive phosphonooxyethyl terminus, making it a versatile intermediate for advanced material synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, pesticides, and plant growth regulators, where the fluorine and phosphorus groups contribute to efficacy and environmental profile.
• Specialty Polymer Modifier: Acts as a functional monomer or cross-linking agent to introduce flame-retardant or surface-active properties into high-performance fluoropolymers and coatings.
• Ligand and Catalyst Precursor: Employed in organometallic chemistry and catalysis research to create sophisticated ligands for transition metal complexes.
• Surface Treatment Agent: Utilized to modify material surfaces, imparting oil- and water-repellent characteristics due to its fluorinated chain.
• Bioconjugation Chemistry: Finds application in biotech for linking molecules, such as in the development of antibody-drug conjugates (ADCs) or diagnostic probes.

Basic Information

Product Name	Poly(Difluoromethylene), .Alpha.-Fluoro-.Omega.-2-(Phosphonooxy)Ethyl-
CAS No.	65530-61-2
Molecular Formula	CnH2nF2O4P (Contact for specific 'n' value and structure)
Molecular Weight	Contact for details
Synonyms	α-Fluoro-ω-2-(phosphonooxy)ethylpoly(difluoromethylene); 2-[(Poly(difluoromethylene))fluoro]ethyl dihydrogen phosphate; Fluorinated alkyl phosphoester; PFPE-based phosphonic acid ester; Telomer B phosphate derivative; Fluorotelomer phosphate intermediate; F(CF2)nCH2CH2OPO(OH)2 (general representation)
EINECS	Contact for details

Quality Control

Our production of Poly(Difluoromethylene), .Alpha.-Fluoro-.Omega.-2-(Phosphonooxy)Ethyl- adheres to a stringent quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR (¹⁹F, ¹H, ³¹P) for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and incompatibility with fluorides/strong alkalis, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (¹⁹F, ³¹P)
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Fluoride Ion (ISE)	≤ 0.1%
Phosphorus Content	Reported on COA
Average Molecular Weight (GPC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.