Description

(3As,6E,10Z,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-10-Hydroxymethyl-6-Methyl-3-Methylenecyclodeca[B]Furan-2-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a key building block for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological potency.
• Natural Product Synthesis: Serves as a synthetic target or intermediate in the total synthesis of complex natural products with sesquiterpene frameworks.
• Biochemical Probe Development: Utilized in the creation of molecular probes to study specific biological pathways and enzyme interactions.
• Agrochemical Research: Investigated as a lead structure for the development of new plant protection agents with novel modes of action.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce specialized, high-value chemical entities.

Basic Information

Product Name	(3As,6E,10Z,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-10-Hydroxymethyl-6-Methyl-3-Methylenecyclodeca[B]Furan-2-One
CAS No.	65400-30-8
Molecular Formula	C₁₅H₂₀O₃
Molecular Weight	248.32 g/mol
Synonyms	10-Hydroxymethyl-6-methyl-3-methylidene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-2-one; (3aR,6E,10Z,11aR)-rel-2,3,3a,4,5,8,9,11a-Octahydro-10-(hydroxymethyl)-6-methyl-3-methylenecyclodeca[b]furan-2-one; Cyclodeca[b]furan-2-one derivative; Sesquiterpene lactone intermediate; CAS 65400-30-8
EINECS	Contact for details

Quality Control

Our (3As,6E,10Z,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-10-Hydroxymethyl-6-Methyl-3-Methylenecyclodeca[B]Furan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research-grade intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.