Description

Chlorofluorometanesulfonyl Chloride is a highly reactive organosulfur compound that serves as a versatile building block in advanced chemical synthesis. Its value lies in its ability to introduce the chlorofluoromethanesulfonyl group, a key functional moiety for creating molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonyl chloride group enables potent activity.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating specialty polymers, coatings, and materials with specific surface properties.
• Organic Synthesis Reagent: Employed in laboratories and pilot plants for introducing sulfonyl groups and constructing complex heterocyclic compounds.
• Ligand & Catalyst Development: Useful in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Chlorofluorometanesulfonyl Chloride
CAS No.	65269-92-3
Molecular Formula	CCl2F2O2S
Molecular Weight	199.98 g/mol
Synonyms	Dichlorodifluoromethanesulfonyl Chloride; Difluorodichloromethanesulfonyl Chloride; Chlorofluoromethanesulfonyl Chloride; CF2Cl2SO2Cl; Methanesulfonyl chloride, dichlorodifluoro-; 1,1-Dichloro-2,2,2-trifluoroethanesulfonyl chloride (related isomer); Perchlorofluoromethanesulfonyl chloride (common industry name)
EINECS	Contact for details

Quality Control

Our Chlorofluorometanesulfonyl Chloride is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.65 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.