Description

4-Methylpent-2-Ynoic Acid is a specialized alkyne-substituted carboxylic acid building block with significant synthetic utility. Its unique structure, featuring both a terminal alkyne and a carboxylic acid functional group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, polymer science, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating molecules with alkyne handles for click chemistry or further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific alkyne-acid motifs.
• Polymer & Material Science: Serves as a monomer or co-monomer for producing specialty polymers, coatings, and resins with tailored properties, such as modified solubility or reactivity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for coupling reactions (e.g., Sonogashira, esterification, amidation) to introduce the 4-methylpent-2-ynoyl moiety.
• Ligand & Catalyst Development: Useful for synthesizing novel chelating ligands or organometallic complexes used in catalysis and material design.
• Chemical Biology Probes: Acts as a precursor for synthesizing probes and tags used in bioconjugation and labeling studies due to its reactive alkyne group.

Basic Information

Product Name	4-Methylpent-2-Ynoic Acid
CAS No.	65199-69-1
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	4-Methyl-2-pentynoic Acid; 4-Methylpent-2-ynoic Acid; 2-Pentynoic acid, 4-methyl-; 4-Methyl-2-pentynoic acid; 4-Methylpent-2-yn-1-oic acid; 4-Methylpent-2-ynoic acid; 4-Methyl-2-pentynoic acid (CAS 65199-69-1)
EINECS	Contact for details

Quality Control

Our 4-Methylpent-2-Ynoic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.