Description

Leucomycin V, 4(Sup B),9-Diacetate 3-Propanoate is a chemically modified derivative of the leucomycin (kitasamycin) macrolide antibiotic, identified by CAS NO 65178-01-0. This semi-synthetic compound is valued for its role as a key intermediate in pharmaceutical research and development, particularly in the synthesis of novel antimicrobial agents. It is primarily required by pharmaceutical manufacturers and research institutions focused on developing advanced antibiotic formulations and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced macrolide antibiotics and novel therapeutic agents.
• Antimicrobial Research: Used in biochemical and microbiological research to study antibiotic mechanisms of action and resistance.
• Veterinary Medicine Development: Serves as a precursor in the development of veterinary antibiotics for livestock and companion animals.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization studies for the industrial production of related antibiotic compounds.

Basic Information

Product Name	Leucomycin V, 4(Sup B),9-Diacetate 3-Propanoate
CAS No.	65178-01-0
Molecular Formula	C45H73NO17
Molecular Weight	900.06 g/mol
Synonyms	Kitasamycin V 4(Sup B),9-Diacetate 3-Propanoate; Leucomycin A5 V 4(Sup B),9-Diacetate 3-Propanoate; 4(Sup B),9-Diacetyl-3-propionylleucomycin V; 3-O-Propionyl-4(Sup B),9-di-O-acetylleucomycin V; 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A derivative; Antibiotic Kitasamycin V ester; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione 4,9-diacetate 3-propanoate
EINECS	Contact for details

Quality Control

Our Leucomycin V, 4(Sup B),9-Diacetate 3-Propanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade standards suitable for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.