Description

[S-(R*,R*)]-3,3'-Dithiobis[2-Methylpropanoic Acid] is a high-purity chiral dithio compound with a defined stereochemistry, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce a specific, stable disulfide linkage and chiral center into target molecules, enabling the development of pharmaceuticals and specialty chemicals with precise structural and functional properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable, high-quality source for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological disorders.
• Peptide Chemistry: Used to create disulfide bridges in peptide synthesis, which are crucial for stabilizing the three-dimensional structure of therapeutic peptides and proteins.
• Ligand Synthesis: Acts as a building block for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Bioconjugation: Employed in the development of linker molecules for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Material Science: Serves as a cross-linking agent or monomer in the production of specialty polymers with unique mechanical or responsive properties.
• Agrochemical Research: Utilized as an intermediate in the development of novel, more effective pesticides and herbicides with specific modes of action.

Basic Information

Product Name	[S-(R*,R*)]-3,3'-Dithiobis[2-Methylpropanoic Acid]
CAS No.	65134-74-9
Molecular Formula	C8H14O4S2
Molecular Weight	238.32 g/mol
Synonyms	Dithiodivaleric Acid; 3,3'-Dithiobis(2-methylpropanoic Acid); (R,R)-Dithiodivaleric Acid; Bis(2-methylpropanoic Acid) Disulfide; 2-Methyl-3,3'-dithiodipropionic Acid; (R,R)-3,3'-Dithiobis(2-methylpropionic Acid); Lipoic Acid Derivative Intermediate; 2,2'-Dimethyl-3,3'-dithiodipropionic Acid
EINECS	Contact for details

Quality Control

Our [S-(R*,R*)]-3,3'-Dithiobis[2-Methylpropanoic Acid] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.