Description

2-Bromo-5-Nitroacetophenone is a versatile halogenated nitroaromatic ketone that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine and nitro functional groups, which enable precise chemical transformations for building complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted acetophenone or aniline moieties.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents where its halogen and nitro groups facilitate further derivatization.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution reactions to create novel organic compounds for research and development.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex azo dyes and other colored compounds.

Basic Information

Product Name	2-Bromo-5-Nitroacetophenone
CAS No.	65130-31-6
Molecular Formula	C8H6BrNO3
Molecular Weight	244.04 g/mol
Synonyms	1-(2-Bromo-5-nitrophenyl)ethanone; 2'-Bromo-5'-nitroacetophenone; 2-Bromo-5-nitroacetophenone; α-Bromo-5-nitroacetophenone; Ethanone, 1-(2-bromo-5-nitrophenyl)-; 2-Bromo-5-nitroacetylbenzene; 1-Acetyl-2-bromo-5-nitrobenzene; 2-Bromo-5-nitro-1-acetylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Nitroacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.