Description

1-(3-Fluoro-1-Naphthalenyl)-Ethanone is a specialized fluorinated aromatic ketone building block, recognized for its unique structural motif that combines a naphthalene core with a ketone and fluorine substituent. This compound is valued for its role as a key intermediate in advanced organic synthesis, enabling the introduction of complex fluorinated aromatic systems. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the fluorine atom can enhance biological activity, metabolic stability, and lipophilicity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and advanced polymers requiring specific fluorinated aromatic components.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for further functionalization to create complex molecular libraries for screening.
• Academic & Industrial R&D: Essential for methodological studies in fluorination chemistry and the exploration of new reaction pathways involving polycyclic aromatic ketones.

Basic Information

Product Name	1-(3-Fluoro-1-Naphthalenyl)-Ethanone
CAS No.	64977-37-3
Molecular Formula	C₁₂H₉FO
Molecular Weight	188.20 g/mol
Synonyms	3'-Fluoro-1'-acetonaphthone; 1-Acetyl-3-fluoronaphthalene; 3-Fluoro-1-naphthyl methyl ketone; 3-Fluoronaphthalen-1-yl ethanone; Ethanone, 1-(3-fluoro-1-naphthalenyl)-; 3-Fluoro-1-acetylnaphthalene; 1-(3-Fluoronaphth-1-yl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-1-Naphthalenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to supply chain integrity and batch-to-batch consistency meets the stringent requirements of research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.