Description

3,21-Dioxooleana-9(11),12-Dien-28-Oic Acid CAS NO 64854-67-7 is a high-purity, semi-synthetic triterpenoid derivative of oleanolic acid, characterized by its specific diketone structure. This compound is a critical advanced pharmaceutical intermediate valued for its role in the synthesis of novel bioactive molecules and drug candidates. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing anti-inflammatory, antiviral, and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: Key starting material or building block for the synthesis of novel triterpenoid-based drug candidates.
• Anti-inflammatory Research: Used in preclinical studies to develop new agents targeting inflammatory pathways, such as NF-κB inhibition.
• Antiviral Agent Development: Investigated as a precursor for compounds with potential activity against viruses like HIV and hepatitis.
• Metabolic Disorder Therapeutics: Serves as a scaffold in research for diabetes and obesity treatment candidates.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and signal transduction pathways.
• Natural Product Derivatization: Used to create semi-synthetic analogs of oleanolic acid with enhanced bioavailability or potency.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3,21-Dioxooleana-9(11),12-Dien-28-Oic Acid
CAS No.	64854-67-7
Molecular Formula	C30H42O4
Molecular Weight	466.65 g/mol
Synonyms	3,21-Dioxoolean-9(11),12-dien-28-oic Acid; Oleana-9(11),12-diene-3,21-dione-28-oic Acid; 3,21-Diketone of Oleanolic Acid; 3,21-Dioxo Oleanolic Acid Derivative; (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4a,5,6,6a,6b,7,8,8a,9,12,12a,14,14a,14b-hexadecahydropicene-2,10-dione-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3,21-Dioxooleana-9(11),12-Dien-28-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.