Description

2-Amino-1-[3-(Trifluoromethyl)Phenyl]Ethanone is a specialized aromatic ketone building block featuring both an amino and a trifluoromethyl group, offering unique reactivity and physicochemical properties. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers with tailored properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on introducing fluorine atoms into complex molecular architectures.

Basic Information

Product Name	2-Amino-1-[3-(Trifluoromethyl)Phenyl]Ethanone
CAS No.	64748-87-4
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)-2-aminoethanone; 2-Amino-1-(3-trifluoromethylphenyl)ethanone; 2-Amino-1-(α,α,α-trifluoro-m-tolyl)ethanone; 3'-Trifluoromethylphenacylamine; m-Trifluoromethylphenacylamine; 2-Amino-1-(3-(trifluoromethyl)phenyl)ethan-1-one; α-Amino-3'-(trifluoromethyl)acetophenone
EINECS	Contact for details

Quality Control

Our 2-Amino-1-[3-(Trifluoromethyl)Phenyl]Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.