Description

6-Acetyl-7-Deacetylforskolin is a semi-synthetic derivative of the natural diterpenoid forskolin, designed to offer enhanced stability and specific biological activity. This compound is a valuable research-grade biochemical tool, primarily utilized for its role in modulating adenylate cyclase and cyclic AMP (cAMP) signaling pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for studies in cell biology, metabolic regulation, and drug discovery.

Application

• Biochemical Research: A key tool for studying cAMP-dependent signal transduction pathways and adenylate cyclase activation in vitro.
• Pharmaceutical R&D: Used as a reference standard and an intermediate in the development of novel therapeutic agents targeting metabolic and cardiovascular diseases.
• Cell Biology Studies: Employed to investigate cellular processes such as lipolysis, hormone secretion, and ion channel regulation.
• Academic Research: Serves as a critical reagent in university and institutional labs for fundamental research in molecular pharmacology.
• High-Throughput Screening (HTS): Utilized in assay development and screening libraries for drug discovery campaigns.
• Metabolic Research: Applied in studies exploring the regulation of glucose and lipid metabolism.

Basic Information

Product Name	6-Acetyl-7-Deacetylforskolin
CAS No.	64657-21-2
Molecular Formula	C24H34O7
Molecular Weight	434.52 g/mol
Synonyms	7-Deacetyl-6-acetylforskolin; 6-Acetyl-7-deacetyl-forskolin; 1α,6β,9α-Trihydroxy-8,13-epoxy-labd-14-en-11-one, 6-acetate; 6-O-Acetyl-7-deacetylforskolin; Colforsin 6-acetate derivative; 6-Ac-7-dAFSK; 6-Ac-7-dAF; Forskolin derivative 64657-21-2
EINECS	Contact for details

Quality Control

Our 6-Acetyl-7-Deacetylforskolin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.