Description

2-(Chloromethyl)-5-(4-Chlorophenyl)1,3-Oxazole, 97+% is a high-purity, functionalized oxazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its dual reactive sites—the chloromethyl group and the oxazole core—which enable its use in constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-quality building block for drug discovery and fine chemical synthesis. CAS No. 64640-12-6.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated oxazole system.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemistry programs, enabling the introduction of the 5-aryloxazole motif into target molecules.

Basic Information

Product Name	2-(Chloromethyl)-5-(4-Chlorophenyl)1,3-Oxazole, 97+%
CAS No.	64640-12-6
Molecular Formula	C10H7Cl2NO
Molecular Weight	228.07 g/mol
Synonyms	5-(4-Chlorophenyl)-2-(chloromethyl)oxazole; 2-(Chloromethyl)-5-(p-chlorophenyl)oxazole; 2-Chloromethyl-5-(4-chlorophenyl)oxazole; 5-(4-Chlorophenyl)-2-(chloromethyl)-1,3-oxazole; Oxazole, 2-(chloromethyl)-5-(4-chlorophenyl)-; NSC 405124; 64640-12-6
EINECS	Contact for details

Quality Control

Every batch of our 2-(Chloromethyl)-5-(4-Chlorophenyl)1,3-Oxazole is produced and tested under a strict quality management system to ensure consistent purity and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material meets the exacting standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if frequent access is required. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.