Description

3α,7α,12α-Tris(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is a high-purity, synthetic steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of modified bile acids and other complex steroid-based molecules, enabling precise structural modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic studies, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and therapeutic agents targeting metabolic pathways.
• Biochemical Research: Used as a reference standard or precursor in studies of bile acid metabolism, liver function, and cholesterol homeostasis.
• Drug Discovery: Serves as a versatile scaffold for medicinal chemists to create new chemical entities with potential biological activity.
• Metabolite Synthesis: Employed in the laboratory-scale production of specific bile acid metabolites for analytical and biological testing.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and steroid biochemistry.

Basic Information

Product Name	3α,7α,12α-Tris(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester
CAS No.	64595-20-6
Molecular Formula	C₂₉H₄₄O₇
Molecular Weight	516.66 g/mol
Synonyms	Methyl 3α,7α,12α-Triacetoxy-24-nor-5β-cholan-23-oate; 24-Nor-5β-cholan-23-oic acid, 3,7,12-tris(acetyloxy)-, methyl ester, (3α,5β,7α,12α)-; Methyl 3α,7α,12α-triacetoxy-24-norcholan-23-oate; Trisnorcholanic acid methyl ester triacetate; 3α,7α,12α-Triacetoxy-24-nor-5β-cholan-23-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3α,7α,12α-Tris(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and traceable material for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.