Description

L-Tryptophan, n-((5-Chloro-3,4-Dihydro-3-Methyl-1-Oxo-1H-2-Benzopyran- 7-Yl)Carbonyl)- is a specialized synthetic derivative of the essential amino acid L-tryptophan, modified with a complex heterocyclic moiety. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key synthetic intermediate or a pharmacologically active scaffold. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, such as enzyme inhibitors or receptor modulators. The precise structural modification offers unique properties for targeted biological activity studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate tryptophan metabolism pathways and related biochemical mechanisms.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new analogs with optimized potency and selectivity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification via HPLC or LC-MS.
• Preclinical Development: Utilized in early-stage in vitro and in vivo studies to assess the pharmacokinetic and pharmacodynamic profile of new chemical entities.

Basic Information

Product Name	L-Tryptophan, n-((5-Chloro-3,4-Dihydro-3-Methyl-1-Oxo-1H-2-Benzopyran- 7-Yl)Carbonyl)-
CAS No.	64398-34-1
Molecular Formula	C22H19ClN2O5
Molecular Weight	426.85 g/mol
Synonyms	N-[(5-Chloro-3,4-dihydro-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-L-tryptophan; 7-[[(2S)-2-Amino-3-(1H-indol-3-yl)-1-oxopropyl]carbamoyl]-5-chloro-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one; L-Tryptophan, N-[(5-chloro-3,4-dihydro-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-; Tryptophan derivative 64398-34-1; 1H-2-Benzopyran-1-one, 7-[[(2S)-2-amino-3-(1H-indol-3-yl)-1-oxopropyl]carbamoyl]-5-chloro-3,4-dihydro-3-methyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.