Description

(3Ar)-3Aα,4,4Aα,7,8,8A,9,9Aα-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a high-purity, specialized sesquiterpene lactone derivative with a complex polycyclic structure. This compound is valued for its role as a critical synthetic intermediate and a scaffold for advanced chemical research and development. It is primarily sought by professionals in the pharmaceutical, agrochemical, and fine chemical sectors for applications in process chemistry, medicinal chemistry, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex natural product analogs and potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Agrochemical Synthesis: Acts as a precursor in the development of novel pesticides or herbicides with specific biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, low-volume specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: Utilized in organic synthesis laboratories for methodological development and exploring new chemical transformations.
• Material Science Precursor: Investigated for the synthesis of specialized polymers or organic electronic materials due to its rigid, fused-ring structure.

Basic Information

Product Name	(3Ar)-3Aα,4,4Aα,7,8,8A,9,9Aα-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	64395-76-2
Molecular Formula	C₁₅H₂₀O₂
Molecular Weight	232.32 g/mol
Synonyms	5,8aβ-Dimethyl-3-methylenedecahydronaphtho[2,3-b]furan-2(3H)-one; 3-Methylene-5,8a-dimethyl-3a,4,4a,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one; (3aR,4S,4aS,8aR,9aS)-3a,4,4a,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one; Alantolactone isomer; Isoalantolactone related compound; Sesquiterpene lactone derivative
EINECS	Contact for details

Quality Control

Our (3Ar)-3Aα,4,4Aα,7,8,8A,9,9Aα-Octahydro-5,8Aβ-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.