Description

[1,8]Naphthyridine-2-Carbaldehyde is a versatile heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, serving as a key precursor for constructing complex nitrogen-containing molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antibacterial agents, and other bioactive nitrogen heterocycles.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Chemical Library Production: Used in combinatorial and parallel synthesis for high-throughput screening and hit-to-lead optimization.

Basic Information

Product Name	[1,8]Naphthyridine-2-Carbaldehyde
CAS No.	64379-45-9
Molecular Formula	C9H6N2O
Molecular Weight	158.16 g/mol
Synonyms	1,8-Naphthyridine-2-carboxaldehyde; 2-Formyl-1,8-naphthyridine; 1,8-Naphthyridine-2-carbaldehyde; 1,8-Naphthyridine-2-carboxylic aldehyde; 2-Aldehyde-1,8-naphthyridine; 1,8-Naphthyridin-2-yl-methanal; 1,8-Naphthyridine-2-aldehyde
EINECS	Contact for details

Quality Control

Our [1,8]Naphthyridine-2-Carbaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant methods is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.