Description

6"-o-Acetylsaikosaponin D is a specific, acetylated derivative of the bioactive triterpenoid saponin, Saikosaponin D, which is primarily sourced from the roots of *Bupleurum* species. This chemical modification is significant as it can alter the compound's solubility, bioavailability, and pharmacological activity profile, making it a valuable reference standard and research intermediate. It is essential for researchers and developers in the pharmaceutical, biotechnology, and natural product sectors who are investigating novel therapeutic agents, metabolic pathways, or require high-purity compounds for analytical and bioactivity studies.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the qualitative and quantitative analysis of Saikosaponin derivatives in raw materials, herbal extracts, and finished products via HPLC, LC-MS, or TLC.
• Biomedical Research: Serves as a key intermediate or active probe in pharmacological studies to investigate anti-inflammatory, hepatoprotective, antiviral, or immunomodulatory mechanisms.
• Natural Product Chemistry: Employed in semi-synthesis to create novel saponin analogs with potentially enhanced or targeted biological activities for drug discovery programs.
• Quality Control & Standardization: Critical for ensuring batch-to-batch consistency and potency in the manufacture of standardized botanical extracts, particularly those derived from *Bupleurum*.
• Academic Research: Used in university and institutional labs for fundamental studies on triterpenoid biosynthesis, structure-activity relationships (SAR), and natural product isolation techniques.

Basic Information

Product Name	6"-o-Acetylsaikosaponin D
CAS No.	64340-45-0
Molecular Formula	C48H76O17
Molecular Weight	925.1 g/mol
Synonyms	6''-O-Acetylsaikosaponin D; Acetyl Saikosaponin D; 6''-Acetyl Saikosaponin D; Saikosaponin D 6''-acetate; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-O-acetyl-β-D-glucopyranosyl-(1→3)-β-D-fucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→2)-β-D-fucopyranoside
EINECS	Contact for details

Quality Control

Every batch of 6"-o-Acetylsaikosaponin D is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for key parameters including assay purity, identification, and impurity profiles as determined by advanced chromatographic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation or clumping. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.