Description

Saikosaponin E is a bioactive triterpenoid saponin primarily extracted from the roots of *Bupleurum* species, a key botanical in traditional medicine. This high-purity compound is valued for its significant pharmacological potential and serves as a critical reference standard in analytical research and quality control. It is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and herbal extract industries seeking to develop or standardize products with consistent bioactivity.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of Saikosaponin content in herbal drugs and finished products via HPLC or LC-MS.
• Bioactivity Research: Serves as a key investigational compound in preclinical studies exploring anti-inflammatory, hepatoprotective, antiviral, and immunomodulatory mechanisms.
• Nutraceutical Formulation: Incorporated into standardized herbal extracts and dietary supplements where consistent saponin profile is required for efficacy claims.
• Quality Control (QC) & Assurance: Employed by quality control laboratories to calibrate equipment and validate analytical methods for raw material and finished product testing.
• Cosmeceutical Development: Investigated for potential application in topical formulations targeting skin inflammation and aging due to its bioactive properties.

Basic Information

Product Name	Saikosaponin E
CAS No.	64340-44-9
Molecular Formula	C42H68O13
Molecular Weight	780.98 g/mol
Synonyms	Saikosaponin E; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→3)-β-D-fucopyranoside; Chikusetsusaponin IVa; SS-E
EINECS	Contact for details

Quality Control

Our Saikosaponin E is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for research and reference standard use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place at 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.